LC-MS (Xevo G2-XS)

Image
Image of a Waters Xevo G2-XS QTof

MS Staff Member:
John Walsby-Tickle

Location:
Basement MS (00.097)

Booking:
Instrument Booking System

Training required:
Yes

Training prerequisites:
Previous experience or knowledge of LC-MS systems

Instrument description:

The Waters Xevo G2-XS is a bench-top QTOF mass spectrometer, designed for the analysis of a wide range of compounds in complex and challenging samples. The instrument incorporates StepWaveTM ion-transfer optics which increase the efficiency of ion transfer and remove neutral species from the ion beam, increasing sensitivity. The instrument is equiped with an ESI LockSprayTM source to allow accurante mass analysis by direct infusion or by LC. The XS collision cell allows fast and sensitive MS/MS experiments to be performed alongisde conventional experiments. The Acquity UPLC system allows seperation of complex mixtures for small molecule analysis, or desalting for protein analysis.

Typical applications:

High resolution LC-MS, Protein analysis, MS/MS experiments

Agilent GC-MSD User Information

Bruker MALDI Sample Preparation

Combining Trypsin/Chymotrypsin Enzymatic Digestion

GC-MS (Agilent 5977B)

In-Gel Trypsin Enzymatic Digestion

In-solution Chymotrypsin Enzymatic Digestion

In-solution protein digestion

LC-MS (Xevo G2-S)

LC-MS (Xevo G2-XS)

MALDI Oligonucleotide Sample Preparation

MALDI User Information

MALDI-MS (Autoflex)

Nanospray IMS-MS (Synapt)

Native MS Sample Preparation

Oligo LC-MS (Xevo G2)

Preparation of blood plasma for metabolomics

Preparation of cell samples for metabolomics

Preparation of plant samples for metabolomics

Preparation of tissue samples for metabolomics

Rapid Digestion - Promega Trypsin/Lys-C Kit

RP-HPLC Purification of Oligonucleotides

Sample Preparation Protocol for Alternative Ionisation Service

Sample Preparation Protocol for BioAccord 1 Intact Protein Analysis

Sample Preparation Protocol for BioAccords

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