Metabolomics LC-MS (Xevo G2-XS)

Image of a G2-XS with Acquity LC and UPC2 systems

Location:
Basement MS (00.097)

Booking:
Sample submission, contact John Walsby-Tickle for more information

Training required:
Yes

Training prerequisites:
Previous experience using LC-MS or SFC-MS systems

Instrument description:

The Waters Xevo G2-XS is a bench-top QTOF mass spectrometer, designed for the analysis of a wide range of compounds in complex and challenging samples. The instrument incorporates StepWave^TM ion-transfer optics which increase the efficiency of ion transfer and remove neutral species from the ion beam, increasing sensitivity. The instrument is equiped with an ESI LockSpray^TM source to allow accurante mass analysis by direct infusion or by LC. The XS collision cell allows fast and sensitive MS/MS experiments to be performed alongisde conventional experiments. This system used for metabolomics projects. The MS can be used either with a conventional Acquity LC system or a UPC2 for supercritical fluid chromatography.

Typical applications:

High resolution LC-MS, metabolomics, lipidomics

Agilent GC-MSD User Information

Bruker MALDI Sample Preparation

Combining Trypsin/Chymotrypsin Enzymatic Digestion

GC-MS (Agilent 7200)

IC-MS (Q Exactive)

In-Gel Trypsin Enzymatic Digestion

In-solution Chymotrypsin Enzymatic Digestion

In-solution protein digestion

MALDI Oligonucleotide Sample Preparation

MALDI User Information

MassLynx

Metabolomics